研究業績 2021年度 A03 新学術領域「水圏機能材料：環境に調和・応答するマテリアル構築学の創成」

原著論文・解説・総説

2021年度/FY2021
A03計画研究/Planned Research A03

A03-1研究代表者　田中 求  /  A03-1 Principal Investigator, Motomu Tanaka

1. Batuhan Kav, Bruno Demé, Christian Gege, Motomu Tanaka, *Emanuel Schneck, and *Thomas R. Weikl, “Interplay of Trans- and Cis-Interactions of Glycolipids in Membrane Adhesion”, Front. Mol. Biosci., 8, 754654-1/13 (2021). Peer-reviewed, Open Access.
   DOI: 10.3389/fmolb.2021.754654
   Published online: 19 Nov. 2021.
   International Joint Research Paper.
2. Morio Ueno, Munetoyo Toda, Kohsaku Numa, Hiroshi Tanaka, Kojiro Imai, John Bush, Satoshi Teramukai, Naoki Okumura, Noriko Koizumi, Akihisa Yamamoto, Motomu Tanaka, Chie Sotozono, Junji Hamuro, and *Shigeru Kinoshita, “Superiority of Mature Differentiated Cultured Human Corneal Endothelial Cell Injection Therapy for Corneal Endothelial Failure”, Am. J. Ophthalmol., 237, 267-277 (2022). Peer-reviewed, Open Access.
   DOI: 10.1016/j.ajo.2021.11.012
   Published online: 08 Nov. 2021.
   International Joint Research Paper.
3. Akihisa Yamamoto, Yuji Higaki, Judith Thoma, Esther Kimmle, Ryohei Ishige, Bruno Demé, Atsushi Takahara, and *Motomu Tanaka, “Water Modulates the Lamellar Structure and Interlayer Correlation of Poly(perfluorooctyl acrylate) Films: a Specular and Off-specular Neutron Scattering Study”, Polymer J., 54, 57-65 (2022). Peer-reviewed, Open Access.
   DOI: 10.1038/s41428-021-00555-2
   Published online: 27 Sep. 2021.
   International Joint Research Paper.
4. Benjamin Fröhlich, Anil K. Dasanna, Christine Lansche, Julian Czajor, Cecilia P. Sanchez, Marek Cyrklaff, Akihisa Yamamoto, Alister Craig, *Ulrich S. Schwarz, *Michael Lanzer, and *Motomu Tanaka, “Functionalized Supported Membranes for Quantifying Adhesion of P. falciparum-Infected Erythrocytes” Biophys. J., 120, 3315-3328 (2021). Peer-reviewed, Open Access.
   DOI: 10.1016/j.bpj.2021.07.003
   Published online: 09 Jul. 2021.
   A03/A03 Collaboration, International Joint Research Paper.
   Highlited in New and Notable.
5. Julian Czajor, Wasim Abuillan, Dinh Vu Nguyen, Christopher Heidebrecht, Evan A. Mondarte, Oleg V. Konovalov, Tomohiro Hayashi, Delphine Felder-Flesch, Stefan Kaufmann, and *Motomu Tanaka, “Dendronized Oligoethylene Glycols with Posphonate Tweezers for Cell-Repellent Coating of Oxide Surfaces: Coarse-Scale and Nanoscopic Interfacial Forces”, RSC Adv., 11, 17727-17733 (2021). Peer-reviewed, Open Access.
   DOI: 10.1039/D1RA02571F
   Published online: 17 May 2021.
   A02/A03 Collaboration, International Joint Research Paper, Invited Paper.
6. *Motomu Tanaka and Akihisa Yamamoto, “Physical Concepts toward Cell–Material Integration”, “Cell-Inspired Materials and Engineering, Fundamental Biomedical Technologies” D. O. Wang, D. Packwood, Part IV, Springer Cham, pp.199-215 (2021).
   DOI: 10.1007/978-3-030-55924-3_9
   Published online: 16 Apr. 2021.
   International Research Book.

A03-1研究分担者　中畑 雅樹  /  A03-1 Co-Investigator, Masaki Nakahata

A03-2研究代表者　田中 賢  /  A03-2 Principal Investigator, Masaru Tanaka

1. *Taiki Tominaga, Mafumi Hishida, Daiki Murakami, Yoshihisa Fujii, Masaru Tanaka, and *Hideki Seto, “Experimental Evidence of Slow Mode Water in the Vicinity of Poly(ethylene oxide) at Physiological Temperature”, J. Phys. Chem. B, 126, 1758-1767 (2022). Peer-Reviewed
   DOI: 10.1021/acs.jpcb.1c09044
   Published online: 22 Feb. 2022
   A02/A03 Collaboration, Supplementary Cover.
2. *Daiki Murakami, Shin-nosuke Nishimura, Yukiko Tanaka, *Masaru Tanaka, “Observing the Repulsion Layers on Blood-compatible Polymer-grafted Interfaces by Frequency Modulation Atomic Force Microscopy”, Biomaterials Advances, 133, 112596-1/4 (2022).
   DOI: 10.1016/j.msec.2021.112596
   Published online: 01 Feb. 2022.
3. *Kei Nishida, Shin-nosuke Nishimura, and *Masaru Tanaka, “Selective Accumulation to Tumor Cells with Coacervate Droplets Formed from Water-Insoluble Acrylate Polymer”, Biomacromolecules, 23, 1569-1580 (2022).
   DOI: 10.1021/acs.biomac.1c01343
   Published online: 28 Jan. 2022.
   Supplementary Journal Cover.
4. Daiki Murakami, Kosuke Yamazoe, Shin-nosuke Nishimura, Naoya Kurahashi, Tomoya Ueda, Jun Miyawaki, Yuka Ikemoto, *Masaru Tanaka, and *Yoshihisa Harada, “Hydration Mechanism in Blood-Compatible Polymers Undergoing Phase Separation”, Langmuir, 38, 1090-1098 (2022). Peer-reviewed.
   DOI: 10.1021/acs.langmuir.1c02672
   Published online: 7 Jan. 2022.
   A02/A03 Collaboration, Cover Picture.
5. *Kazuki Fukushima, Kodai Matsuzaki, Masashi Oji, Yuji Higuchi, Go Watanabe, Yuki Suzuki, Moriya Kikuchi, Nozomi Fujimura, Naofumi Shimokawa, Hiroaki Ito, Takashi Kato, *Seigou Kawaguchi, and *Masaru Tanaka, “Anisotropic, Degradable Polymer Assemblies Driven by a Rigid Hydrogen-Bonding Motif That Induce Shape-Specific Cell Responses”, Macromolecules, 55, 15-25 (2022). Peer-reviewed.
   DOI: 10.1021/acs.macromol.1c01894
   Published online: 20 Dec. 2021.
   A01/A02/A03 Collaboration.
6. *Shin-nosuke, Nishimura, Kei Nishida, and *Masaru Tanaka, “A β-Hairpin Peptide with pH-Controlled Affinity for Tumor Cells”, Chem. Commun., 58, 505-508 (2022). Peer-reviewed.
   DOI: 10.1039/d1cc06218b
   Published online: 18 Nov. 2021.
   Inside Front Cover Picture.
7. Chiharu Ueda, Junsu Park, Kazuya Hirose, Subaru Konishi, Yuka Ikemoto, Motofumi Osaki, Hiroyasu Yamaguchi, *Akira Harada, *Masaru Tanaka, *Go Watanabe, and *Yoshinori Takashima, “Behavior of Supramolecular Cross-Links Formed by Host-Guest Interactions in Hydrogels Responding to Water Contents”, Supramol. Mater., 1, 100001-1/9 (2022). Peer-reviewed, Open Access.
   DOI: 10.1016/j.supmat.2021.100001
   Published online: 15 Nov. 2021.
   A02/A03 Collaboration.
8. Yoshihisa Fujii, Taiki Tominaga, Daiki Murakami, Masaru Tanaka, and *Hideki Seto, “Local Dynamics of the Hydration Water and Poly(methyl methacrylate) Chains in PMMA Networks”, Front. Chem., 9, 728738-1/8 (2021). Peer-reviewed, Open Access.
   DOI: 10.3389/fchem.2021.728738
   Published online: 29 Oct. 2021.
   A02/A03 Collaboration.
9. Yasunobu Asawa, Kei Nishida, Kazuki Kawai, Kiyotaka Domae, Hyun Seung Ban, Akihiro Kitazaki, Hiroya Asami, Jun-Ya Kohno, Satoshi Okada, Hiraku Tokuma, Daisuke Sakano, Shoen Kume, Masaru Tanaka, and *Hiroyuki Nakamura, “Carborane as an Alternative Efficient Hydrophobic Tag for Protein Degradation”, Bioconjugate Chem., 32, 2377-2385 (2021). Peer-reviewed.
   DOI: 10.1021/acs.bioconjchem.1c00431
   Published online: 26 Oct. 2021.
10. Ryohei Koguchi, Katja Jankova, and *Masaru Tanaka, “Fluorine-Containing Bio-Inert Polymers: Roles of Intermediate Water”, Acta Biomater., 138, 34-56 (2022). Peer-reviewed.
    DOI: 10.1016/j.actbio.2021.10.027
    Published online: 23 Oct. 2021.
    International Joint Research Paper.
11. Ryongsok Chang, Evan Angelo Quimada Mondarte, Debabrata Palai, Taito Sekine, Aki Kashiwazaki, Daiki Murakami, Masaru Tanaka, and *Tomohiro Hayashi, “Protein- and Cell-Resistance of Zwitterionic Peptide-Based Self-Assembled Monolayers: Anti-Biofouling Tests and Surface Force Analysis”, Front. Chem., 9, 748017 (2021). Peer-reviewed, Open Access.
    DOI: 10.3389/fchem.2021.748017
    Published online: 6 Oct. 2021.
    A02/A03 Collaboration.
12. *Tetsuya Ishizawa, *Naohiko Makino, Yasuharu Kakizaki, Akiko Matsuda, Yoshihide Toyokawa, Shun Ooyama, Masaru Tanaka, and Yoshiyuki Ueno, “Biosafety of a Novel Covered Self-expandable Metal Stent Coated with Poly(2-Methoxyethyl Acrylate) in vivo”, PLOS ONE, 16, e0257828-1/10 (2021). Peer-reviewed, Open Access.
    DOI: 10.1371/journal.pone.0257828
    Published online: 24 Sep. 2021.
13. Motofumi Osaki, Shin Yonei, Chiharu Ueda, Ryohei Ikura, Junsu Park, Hiroyasu Yamaguchi, *Akira Harada, *Masaru Tanaka, and *Yoshinori Takashima, “Mechanical Properties with Respect to Water Content of Host–Guest Hydrogels”, Macromolecules, 54, 8067-8076 (2021). Peer-reviewed.
    DOI: 10.1021/acs.macromol.1c00970
    Published online: 27 Aug. 2021.
    A03/A03 Collaboration.
14. Tomoya Ueda, *Daiki Murakami, and *Masaru Tanaka, “Effect of Amount of Hydrated Water and Mobility of Hydrated Poly(2-Methoxyethyl Acrylate) on Denaturation of Adsorbed Fibrinogen”, J. Polym. Sci., 59, 2763-2770 (2021). Peer-reviewed.
    DOI: 10.1002/pol.20210496
    Published online: 25 Aug. 2021.
    Invited Paper.
15. Kei Nishida, Takahisa Anada, Shingo Kobayashi, Tomoya Ueda, and *Masaru Tanaka, “Effect of Bound Water Content on Cell Adhesion Strength to Water-insoluble Polymers”, Acta Biomater., 134, 313-324 (2021). Peer-reviewed.
    DOI: 10.1016/j.actbio.2021.07.058
    Published online: 29 Jul. 2021.
16. Mostofa Mabrouk, Hanan H. Beherei, Yukiko Tanaka, and *Masaru Tanaka, “Investigating the Intermediate Water Feature of Hydrated Titanium Containing Bioactive Glass”, Int. J. Mol. Sci., 22, 8038-1/16 (2021). Peer-reviewed, Open Access.
    DOI: 10.3390/ijms22158038
    Published online: 27 Jul. 2021.
    International Joint Research Paper.
17. Shichen Liu, *Shingo Kobayashi, Shin-nosuke Nishimura, Tomoya Ueda, and *Masaru Tanaka, “Effect of Pendant Groups on the Blood Compatibility and Hydration States of Poly(2-oxazoline)s”, J. Polym. Sci., 59, 2559-2570 (2021). Peer-reviewed.
    DOI: 10.1002/pol.20210410
    Published online: 19 Jul. 2021.
    Invited Paper
18. Rubaiya Anjum, Shin-nosuke Nishimura, Shingo Kobayashi, Kei Nishida, *Takahisa Anada, and *Masaru Tanaka, “Protein Stabilization Effect of Zwitterionic Osmolyte-bearing Polymer”, Chem. Lett., 50, 1699-1702 (2021). Peer-reviewed.
    DOI: 10.1246/cl.210335
    Published online: 14 Jul. 2021.
19. Moe Yamazaki, Yosuke Sugimoto, Daiki Murakami, Masaru Tanaka, and *Tooru Ooya, “Effect of Branching Degree of Dendritic Polyglycerols on Plasma Protein Adsorption: Relationship between Hydration States and Surface Morphology”, Langmuir, 37, 8534-8543 (2021). Peer-reviewed.
    DOI: 10.1021/acs.langmuir.1c01003
    Published online: 05 Jul. 2021.
20. Takuma Kanamaru, Masataka Araki, Rintaro Takahashi, Shota Fujii, Toshiyuki Shikata, Daiki Murakami, Masaru Tanaka, and *Kazuo Sakurai, “First Observation of the Hydration Layer around Polymer Chain by Scattering and Its Relationship to Thromboresistance; Dilute Solution Properties of PMEA in THF/Water”, J. Phys. Chem. B, 125, 7251-7261 (2021). Peer-reviewed.
    DOI: 10.1021/acs.jpcb.1c01864
    Published online: 28 Jun. 2021.
21. *Chiaki Yoshikawa, Shinya Hattori, Chih-Feng Huang, Hisatoshi Kobayashi, and *Masaru Tanaka, “In Vitro and In Vivo Blood Compatibility of Concentrated Polymer Brushes”, J. Mater. Chem. B, 9, 5794-5804 (2021). Peer-reviewed.
    DOI: 10.1039/D1TB00886B
    Published online: 07 Jun. 2021.
22. Shichen Liu, Shingo Kobayashi, Toshiki Sonoda, and *Masaru Tanaka, “Poly(tertiary amide acrylate) (Co)polymers Inspired by Poly(2-oxazoline)s: Their Blood Compatibility and Hydration States”, Biomacromolecules, 22, 2718-2728 (2021). Peer-reviewed.
    DOI: 10.1021/acs.biomac.1c00411
    Published online: 03 Jun. 2021.
    A03/A03 Collaboration.
23. *An-Tsung Kuo, Shingo Urata, Ryohei Koguchi, Toshiki Sonoda, Shingo Kobayashi, and Masaru Tanaka, “Effects of Side-Chain Spacing and Length on Hydration States of the Poly(2-methoxyethyl acrylate) Analogs: A Molecular Dynamics Study”, ACS Biomater. Sci. Eng., 7, 2383-2391 (2021). Peer-reviewed.
    DOI: 10.1021/acsbiomaterials.1c00388
    Published online: 12 May 2021.
    A03/A03 Collaboration.
24. Ayako Tsujimoto, Hiroki Uehara, Haruna Yoshida, Misaki Nishio, Kousuke Furuta, Takashi Inui, Akikazu Matsumoto, Shigeaki Morita, Masaru Tanaka, and *Chie Kojima, “Different Hydration States and Passive Tumor Targeting Ability of Polyethylene Glycol-Modified Dendrimers with High and Low PEG density”, Mater. Sci. Eng. C, 126, 112159-1/7 (2021). Peer-reviewed.
    DOI: 10.1016/j.msec.2021.112159
    Published online: 01 May 2021.
    A02/A03 Collaboration.
25. Rubaiya Anjum, Kei Nishida, Haruka Matsumoto, Daiki Murakami, Shingo Kobayashi, *Takahisa Anada, and *Masaru Tanaka, “Attachment and Growth of Fibroblast Cells on Poly(2-methoxyethyl acrylate) Analog Polymers as Coating Materials”, Coatings, 11, 461-1/16 (2021). Peer-reviewed, Open Access.
    DOI: 10.3390/coatings11040461
    Published online: 16 Apr. 2021.
    A03/A03 Collaboration.

A03-2研究分担者　藤井 義久  /  A03-2 Co-Investigator, Yoshihisa Fujii

1. *Taiki Tominaga, Mafumi Hishida, Daiki Murakami, Yoshihisa Fujii, Masaru Tanaka, and *Hideki Seto, “Experimental Evidence of Slow Mode Water in the Vicinity of Poly(ethylene oxide) at Physiological Temperature”, J. Phys. Chem. B, 126, 1758-1767 (2022). Peer-Reviewed
   DOI: 10.1021/acs.jpcb.1c09044
   Published online: 22 Feb. 2022
   A02/A03 Collaboration, Supplementary Cover.
2. *瀬戸秀紀, 山田武, 富永大輝, 藤井義久, “中性子準弾性散乱による水和水の運動状態解析”, 熱測定, 49, 20-25 (2022).
   *Hideki Seto, Takeshi Yamada, Taiki Tominaga, and Yoshihisa Fujii, “Dynamic Behavior of Hydration Water Investigated by Quasi-Elastic Neutron Scattering”, Netsu Sokutei, 49, 20-25 (2022). (in Japanese)
   Link
   Published online: 25 Jan. 2022.
   A02/A03 Collaboration.
3. Yoshihisa Fujii, Taiki Tominaga, Daiki Murakami, Masaru Tanaka, and *Hideki Seto, “Local Dynamics of the Hydration Water and Poly(methyl methacrylate) Chains in PMMA Networks”, Front. Chem., 9, 728738-1/8 (2021). Peer-reviewed, Open Access.
   DOI: 10.3389/fchem.2021.728738
   Published online: 29 Oct. 2021.
   A02/A03 Collaboration.

A03-3研究代表者　高島 義徳  /  A03-3 Principal Investigator, Yoshinori Takashima

1. Hinako Tsuchiya, Yuki Asaki, Garry Sinawang, Taka-aki Asoh, Motofumi Osaki, Junsu Park, Yuka Ikemoto, Hiroyasu Yamaguchi, *Akira Harada, *Hiroshi Uyama, and *Yoshinori Takashima, “Cellulose Nanofiber Composite Polymeric Materials with Reversible and Movable Cross-links and Evaluation of their Mechanical Properties”, ACS Appl. Polym. Mater., 2021. Peer-reviewed, Open Access.
   DOI: 10.1021/acsapm.1c01332
   Published online: 14 Dec. 2021.
   A02/A03 Collaboration.
2. Chiharu Ueda, Junsu Park, Kazuya Hirose, Subaru Konishi, Yuka Ikemoto, Motofumi Osaki, Hiroyasu Yamaguchi, *Akira Harada, *Masaru Tanaka, *Go Watanabe, and *Yoshinori Takashima, “Behavior of Supramolecular Cross-Links Formed by Host-Guest Interactions in Hydrogels Responding to Water Contents”, Supramol. Mater., 1, 100001-1/9 (2022). Peer-reviewed, Open Access.
   DOI: 10.1016/j.supmat.2021.100001
   Published online: 15 Nov. 2021.
   A02/A03 Collaboration.
3. Motofumi Osaki, Shin Yonei, Chiharu Ueda, Ryohei Ikura, Junsu Park, Hiroyasu Yamaguchi, *Akira Harada, *Masaru Tanaka, and *Yoshinori Takashima, “Mechanical Properties with Respect to Water Content of Host–Guest Hydrogels”, Macromolecules, 54, 8067 (2021). Peer-reviewed.
   DOI: 10.1021/acs.macromol.1c00970
   Published online: 27 Aug. 2021.
   A03/A03 Collaboration.

A03-3研究分担者　松葉 豪  /  A03-3 Co-Investigator, Go Matsuba

1. 松葉 豪, 「放射光X線を用いた高分子構造解析」, 成形加工, 34, 78-81, (2022). (in Japanese)
   Go Matsuba, “Structural Analysis with Synchrotron Radiation X-ray Beams”, J. JSPP, 34, 78-81, (2022). (in Japanese). Open Access.
   DOI: 10.4325/seikeikakou.34.78
   Published online: 01 Mar. 2022.
2. *Yasunori Nakamura, Akiko Kubo, Masami Ono, Kazuki Yashiro, Go Matsuba, Yifei Wang, Akira Matsubara, Goro Mizutani, Junko Matsuki, and Keiji Kainuma, “Changes in Fine Structure of Amylopectin and Internal Structures of Starch Granules in Developing Endosperms and Culms Caused by Starch Branching Enzyme Mutations of Japonica Rice”, Plant Mol. Biol., 108, 481-496 (2022). Peer-reviewed, Open Access.
   DOI: 10.1007/s11103-021-01237-6
   Published online: 31 Jan. 2022.
3. *Youfeng Yue, Yoshiko Yokota, and Go Matsuba, “Polyelectrolyte-Layered Hydrogels with Electrically Tunable Toughness, Viscoelasticity, Hysteresis, and Crack Resistance”, Macromolecules, 55, 4, 1230-1238 (2022). Peer-reviewed.
   DOI: 10.1021/acs.macromol.1c02137
   Published online: 27 Jan. 2022.
   A03/A03 Collaboration.
4. Akane Nagasaki, *Go Matsuba, Yuka Ikemoto, Taro Moriwaki, Noboru Ohta, and Keiichi Osaka, “Analysis of the Sol and Gel Structures of Potato Starch over a Wide Spatial Scale”, Food Sci. Nutr., 9, 4916-4926 (2021). Peer-reviewed, Open Access.
   DOI: 10.1002/fsn3.2441
   Published online: 21 Jul. 2021.
   A02/A03 Collaboration.

2021年度     /   FY2021
A03公募研究  /   Publicly Offered Research A03

A03研究代表者　相良 剛光  /  A03 Principal Investigator, Yoshimitsu Sagara

1. Tatsuya Muramatsu, Yuji Okado, Hanna Traeger, Stephen Schrettl, Nobuyuki Tamaoki, *Christoph Weder, and *Yoshimitsu Sagara, “Rotaxane-Based Dual Function Mechanophores Exhibiting Reversible and Irreversible Responses”, J. Am. Chem. Soc., 143, 9884-9892 (2021). Peer-reviewed.
   DOI: 10.1021/jacs.1c03790
   Published online: 24 Jun. 2021.
   International Joint Research Paper.
   Press Release by JST and Tokyo Institute of Technology.
2. Shohei Shimizu, Shakkeeb Thazhathethil, *Kiyonori Takahashi, Takayoshi Nakamura and *Yoshimitsu Sagara, “Crystal Structure of a 1,6-Bis(phenylethynyl)pyrene-Based Cyclophane That Exhibits Mechanochromic Luminescence”, Mol. Syst. Des. Eng., 6, 1039-1046 (2021). Peer-reviewed.
   DOI: 10.1039/d1me00131k
   Published online: 29 Sep. 2021.
   Invited Paper.

A03研究代表者　稲川 有徳  /  A03 Principal Investigator, Arinori Inagawa

1. *Arinori Inagawa, Miwa Kimura, and Nobuo Uehara, “Total Protein Assay by PCA-Based RGB-Spectrum Conversion Methods with Smartphone-acquired Digital Images”, Anal. Sci., 38, 869-880 (2022). Peer-reviewed.
   DOI: 10.1007/s44211-022-00107-5
   Published online: 24 Mar. 2022.
2. *Arinori Inagawa, Minami Maeda, and Nobuo Uehara, “In situ Visualization of Ferrous Ions Dissolved from Pure Iron Wire into Thin Frozen Aqueous Solution Films by Combination of Microscopy and Image Processing”, Sens. Mater., 34, 915-925 (2022). Peer-reviewed.
   DOI: 10.18494/SAM.2021.3448
   Published online: 22 Mar. 2022.
   
3. *Arinori Inagawa, Kana Saito, Mao Fukuyama, Munenori Numata, and Nobuo Uehara, “Geometrical pH Mapping of Microfluids by Principal-component-analysis-based xyz-spectrum Conversion Method”, Anal. Chim. Acta, 1182, 338952 (2021). Peer-reviewed.
   DOI: 10.1016/j.aca.2021.338952
   Published online: 16 Aug. 2021.

A03研究代表者　桶葭 興資  /  A03 Principal Investigator, Kosuke Okeyoshi

1. Kulisara Budpud, *Kosuke Okeyoshi, Shoko Kobayashi, Maiko K. Okajima, and *Tatsuo Kaneko, “Super-Moisturizing Materials from Morphological Deformation of Suprapolysaccharides”, Macromol. Rapid Comun., 43, 2200163-1/8 (2022). Peer-reviewed.
   DOI: 10.1002/marc.202200163
   Published online: 26 Mar. 2022.
   Cover Picture.

A03研究代表者　竹田 一旗  /  A03 Principal Investigator, Kazuki Takeda

A03研究代表者　松本 拓也  /  A03 Principal Investigator, Takuya Matsumoto

A03研究代表者　松本 卓也  /  A03 Principal Investigator, Takuya Matsumoto

1. Mahmoud Farahat, Emilio Satoshi Hara, Risa Anada, Gulsan Ara Sathi Kazi, Nahid Akhter, and *Takuya Matsumoto, “Mechanotransductive Mechanisms of Biomimetic Hydrogel Cues Modulating Meckel’s Cartilage Degeneration”, Adv. Biol., 6, e2101315 (2022). Peer-reviewed, Open Access.
   DOI: 10.1002/adbi.202101315
   Published online: 28 Mar. 2022.
2. Atsushi Yabe, *Masahiro Okada, Emilio Satoshi Hara, Yasuhiro Torii, and *Takuya Matsumoto, “Self-Adhering Implantable Device of Titanium: Enhanced Soft-Tissue Adhesion by Sandblast Pretreatment”, Colloids Surf. B. Biointerfaces, 211, 112283 (2022). Peer-reviewed.
   DOI: 10.1016/j.colsurfb.2021.112283
   Published online: 10 Dec. 2021.
3. Yaming Wang, *Masahiro Okada, Shi Chao Xie, Yu Yang Jiao, Emilio Satoshi Hara, Hiroaki Yanagimoto, Takumi Fukumoto, and *Takuya Matsumoto, “Immediate Soft-Tissue Adhesion and the Mechanical Properties of the Ti–6Al–4V Alloy after Long-Term Acid Treatment”, J. Mater. Chem. B., 9, 8348-8354 (2021). Peer-reviewed.
   DOI: 10.1039/D1TB00919B
   Published online: 27 Aug. 2021.

A03研究代表者　都留 稔了  /  A03 Principal Investigator, Toshinori Tsuru

1. Norihiro Moriyama, Misato Ike, Hiroki Nagasawa, Masakoto Kanezashi, and *Toshinori Tsuru, “Network Tailoring of Organosilica Membranes via Aluminum Doping to Improve the Humid-Gas Separation Performance”, RSC Adv., 12, 5834-5846 (2022). Peer-reviewed, Open Access.
   DOI: 10.1039/d1ra07866f
   Published online: 16 Feb. 2022.
2. Norihiro Moriyama, Hiroki Nagasawa, Masakoto Kanezashi, and *Toshinori Tsuru, “Steam Recovery via Nanoporous and Subnanoporous Organosilica Membranes: The Effects of Pore Structure and Operating Conditions” Sep. Purif. Technol., 275, 119191-1/10 (2021). Peer-reviewed.
   DOI: 10.1016/j.seppur.2021.119191
   Published online: 27 Jun. 2021.
3. Takashi Terao, Hiroki Nagasawa, Masakoto Kanezashi, Hiroshi Yanagishita, and *Toshinori Tsuru, “Controlled Organosilica Networks via Metal Doping for Improved Dehydration Membranes with Layered Hybrid Structures”, Sep. Purif. Technol., 278, 119561-1/10 (2022). Peer-reviewed.
   DOI: 10.1016/j.seppur.2021.119561
   Published online: 25 Aug. 2021.
4. *都留稔了, “アモルファス構造を有するサブナノ多孔膜の開発と分離特性”, 分離技術会, 50, 289-297 (2020)
   Toshinori Tsuru, “Development of Amorphpus Subnanoporous Membranes for Molecular Separation”, Bunri gijyutsu, 50, 289-297 (2020) (in Japanese)
   Link
5. Takashi Terao, Hiroki Nagasawa, Masakoto Kanezashi, Hiroshi Yanagishita, and *Toshinori Tsuru, “Controlled Organosilica Networks via Metal Doping for Improved Dehydration Membranes with Layered Hybrid Structures”, Sep. Purif. Technol., 278, 119561-1/10 (2022). Peer-reviewed.
   DOI: 10.1016/j.seppur.2021.119561
   Published online: 25 Aug. 2021.

A03研究代表者　児島 千恵  /  A03 Principal Investigator, Chie Kojima

1. *児島千恵, “医薬品DDSへの活用のためのデンドリマーの利点と課題”, 医薬品におけるDDS技術開発と製剤への応用，第5章第２節, 情報機構, pp. 271-285 (2021).
   *Chie Kojima, “Advantages and Problems of Dendrimers for the Application of DDS Medicine”, Development of DDS Technology in Pharmaceutics and Application to Pharmaceutical Formulation, Chapter 5, Section 2, Johokiko, pp. 271-285 (2021). (in Japanese)
   https://johokiko.co.jp/publishing/BA211203.php
   Published: 23 Dec. 2021.
2. *Chie Kojima, Hai Xia, Yojiro Yamamoto, and Hiroshi Shiigi, “A Naked-Eye Colorimetric pH and Temperature Sensor Based on Gold Nanoparticle-Loaded Stimuli-Sensitive Dendrimers”, ChemNanoMat, 8, e202100442-1/6 (2022). Peer-reviewed, Open Access.
   DOI: 10.1002/cnma.202100442
   Published online: 14 Dec. 2021.
   Cover Picture.
   Press Release by Osaka Prefecture University.
3. Hiroya Shiba, Misaki Nishio, Mei Sawada, Mamiko Tamaki, Masataka Michigami, Shinya Nakai, Ikuhiko Nakase, Ikuo Fujii, Akikazu Matsumoto, and *Chie Kojima, “Carboxy-Terminal Dendrimers with Phenylalanine for pH-Sensitive Delivery System into Immune Cells Including T Cells”, J. Mater. Chem. B, 10, 2463-2470 (2022). Peer-reviewed.
   DOI: 10.1039/D1TB01980E
   Published online: 07 Dec. 2021.
   Cover Picture.
   Press Release by Osaka Metropolitan University.
4. *児島千恵, “多分岐ポリマーを用いた温度応答性高分子の合成”, 刺激応答性高分子の開発動向, 第２編第３章, シーエムシー出版, pp. 25-32 (2021).
   *Chie Kojima, “Synthesis of Thermosensitive Polymers Using Highly Branched Polymers”, Development Trend of Stimuli-Responsive Polymers, Part 2, Chapter 3, CMC Publishing, pp. 25-32 (2021). (in Japanese)
   https://www.cmcbooks.co.jp/products/detail.php?product_id=8286
   Published: 21 Jul. 2021.
5. Ayako Tsujimoto, Hiroki Uehara, Haruna Yoshida, Misaki Nishio, Kosuke Furuta, Takashi Inui, Akikazu Matsumoto, Shigeaki Morita, Masaru Tanaka, and *Chie Kojima, “Different Hydration States and Passive Tumor Targeting Ability of Polyethylene Glycol-Modified Dendrimers with High and Low PEG Density”, Mater. Sci. Eng. C, 126, 112159-1/7 (2021). Peer-reviewed.
   DOI: 10.1016/j.msec.2021.112159
   Published online: 01 May 2021.
   A02/A03 Collaboration.

A03研究代表者　長瀬 健一  /  A03 Principal Investigator, Kenichi Nagase

1. *Kenichi Nagase, Kosuke Matsumoto, and Hideko Kanazawa, “Temperature-Responsive Mixed-Mode Column for the Modulation of Multiple Interactions”, Sci. Rep., 12(1), 4434-1/13 (2022). Peer-reviewed.
   DOI: 10.1038/s41598-022-08475-8
   Published online: 15 Mar. 2022.
2. *Kenichi Nagase, So Inoue, Masakazu Inoue, and Hideko Kanazawa, “Two-Dimensional Temperature-Responsive Chromatography Using a Poly(N-isopropylacrylamide) Brush-Modified Stationary Phase for Effective Therapeutic Drug Monitoring”, Sci. Rep., 12(1), 2653-1/13 (2022). Peer-reviewed.
   DOI: 10.1038/s41598-022-06638-1
   Published online: 16 Feb. 2022.
3. *Kenichi Nagase, Sakiko Kitazawa, Toshihiko Kogure, Sota Yamada, Kazuhiro Katayama, and Hideko Kanazawa, “Viral Vector Purification with Thermoresponsive-Anionic Mixed Polymer Brush Modified Beads-Packed Column”, Sep. Purif. Technol., 286, 120445-1/11 (2022). Peer-reviewed.
   DOI: 10.1016/j.seppur.2022.120445
   Published online: 05 Jan. 2022.
4. *Kenichi Nagase, Teruno Nishiyama, Masakazu Inoue, and Hideko Kanazawa, “Temperature Responsive Chromatography for Therapeutic Drug Monitoring with An Aqueous Mobile Phase”, Sci. Rep., 11, 23508-1/12 (2021) Peer-reviewed, Open Access.
   DOI: 10.1038/s41598-021-02998-2
   Published online: 06 Dec. 2021.
5. *Kenichi Nagase, “Thermoresponsive Interfaces Obtained Using Poly(N-Isopropylacrylamide)-Based Copolymer for Bioseparation and Tissue Engineering Applications”, Adv. Colloid Interface Sci., 295, 102487-1/24 (2021). Peer-reviewed, Open Access.
   DOI: 10.1016/j.cis.2021.102487
   Published online: 14 Jul. 2021.
6. *Kenichi Nagase, Goro Edatsune, Yuki Nagata, Junnosuke Matsuda, Daiju Ichikawa, Sota Yamada, Yutaka Hattori, and Hideko Kanazawa, “Thermally-Modulated Cell Separation Columns Using a Thermoresponsive Block Copolymer Brush as a Packing Material for the Purification of Menchymal Stem Cells”, Biomater. Sci., 9 7054-7064 (2021). Peer-reviewed.
   Cover.
   DOI: 10.1039/D1BM00708D
   Published online: 07 Jul. 2021.
7. *Kenichi Nagase, Yuta Ishizawa, Masakazu Inoue, Matsurika Kokubun, Sota Yamada, and Hideko Kanazawa, “Temperature-Responsive Spin Column for Sample Preparation Using An All-Aqueous Eluent”, Anal. Chim. Acta, 1179, 338806 (2021). Peer-reviewed.
   DOI: 10.1016/j.aca.2021.338806
   Published online: 28 Jun. 2021.
8. *Kenichi Nagase, Yuta Umemoto, and Hideko Kanazawa, “Effect of Pore Diameter on the Elution Behavior of Analytes from Thermoresponsive Polymer Grafted Beads Packed Columns”, Sci. Rep., 11, 9976-1/11 (2021). Peer-reviewed, Open Access.
   DOI: 10.1038/s41598-021-89165-9
   Published online: 11 May 2021.

A03研究代表者　羽曾部 卓  /  A03 Principal Investigator, Taku Hasobe

1. *Taku Hasobe, Shunta Nakamura, *Nikolai V. Tkachenko, and *Yasuhiro Kobori, “Molecular Design Strategy for High-Yield and Long-Lived Individual Doubled Triplet Excitons through Intramolecular Singlet Fission”, ACS Energy Lett., 7, 390-400 (2022). Peer-reviewed.
   DOI: 10.1021/acsenergylett.1c02300
   Published online: 27 Dec. 2021.
   International Joint Research Paper, Invited Paper.
2. Shunta Nakamura, Hayato Sakai, Hiroki Nagashima, Masaaki Fuki, Kakeru Onishi, Ramsha Khan, *Yasuhiro Kobori, *Nikolai V. Tkachenko, and *Taku Hasobe, “Synergetic Role of Conformational Flexibility and Electronic Coupling for Quantitative Intramolecular Singlet Fission”, J. Phys. Chem. C, 125, 18287-18296 (2021). Peer-reviewed.
   DOI: 10.1021/acs.jpcc.1c04734
   Published online: 13 Aug. 2021.
   International Joint Research Paper.
3. Nakamura Shunta, Hayato Sakai, Masaaki Fuki, *Yasuhiro Kobori, *Nikolai V. Tkachenko, and *Taku Hasobe, “Enthalpy–Entropy Compensation Effect for Triplet Pair Dissociation of Intramolecular Singlet Fission in Phenylene Spacer-Bridged Hexacene Dimers”, J. Phys. Chem. Lett., 12, 6457-6463 (2021). Peer-reviewed.
   DOI: 10.1021/acs.jpclett.1c01430
   Published online: 08 Jul. 2021.
   International Joint Research Paper.
4. Lorenzo Catti, Haruna Narita, Yuya Tanaka, *Hayato Sakai, Taku Hasobe, *Nikolai Tkachenko, and *Michito Yoshizawa, “Supramolecular Singlet Fission of Pentacene Dimers within Polyaromatic Capsules”, J. Am. Chem. Soc., 143, 9361-9367 (2021). Peer-reviewed.
   DOI: 10.1021/jacs.0c13172
   Published online: 16 Jun. 2021.
   International Joint Research Paper.

A03研究代表者　宮田 隆志  /  A03 Principal Investigator, Takashi Miyata

1. Masaaki Okihara, Kohei Okuma, Akifumi Kawamura, and *Takashi Miyata, “Photoresponsive Gelation of Four-Armed Poly(ethylene glycol) with Photodimerizable Groups”, Gels, 8, 183-1/12 (2022). Peer-reviewed, Open Access.
   DOI: 10.3390/gels8030183
   Published online: 16 Mar. 2022.
2. Takafumi Noguchi, Nobuhiro Akioka, Yuri Kojima, Akifumi Kawamura, and *Takashi Miyata, “Photoresponsive Polymer Films with Directly Micropatternable Surface Based on the Change in Free Volume by Photo-crosslinking”, Adv. Mater. Interfaces, 9, 2101965 (2022). Peer-reviewed.
   DOI: 10.1002/admi.202101965
   Published online: 05 Jan. 2022.
3. *Akifumi Kawamura, Ayaka Harada, Shunsuke Ueno, and *Takashi Miyata, “Weakly Acidic pH and Reduction Dual Stimuli-Responsive Gel Particles”, Langmuir, 37, 11484-11492 (2021). Peer-reviewed.
   DOI: 10.1021/acs.langmuir.1c01677
   Published online: 25 Sep. 2021.
4. *宮田隆志, “刺激応答性高分子の研究動向”, 刺激応答性高分子の研究動向，第2章, シーエムシー出版, pp. 9-23 (2021).
   *Takashi Miyata, “Recent Trends in Stimuli-responsive Polymers”, Recent Developments in Stimuli-Responsive Polymers, Chapter 2, CMC, pp. 9-23 (2021). (in Japanese)
   Link
   Published online: 21 Jul. 2021.
5. Chisa Norioka, Yuino Inamoto, Chika Hajime, Akifumi Kawamura, and *Takashi Miyata, “A Universal Method to Easily Design Tough and Stretchable Hydrogels”, NPG Asia Materials, 13, 34-1/10 (2021). Peer-reviewed, Open Access.
   DOI: 10.1038/s41427-021-00302-2
   Published online: 09 Apr. 2021.
   Press Release by Kansai University.

A03研究代表者　楽 優鳳  /  A03 Principal Investigator, Youfeng Yue

1. *Youfeng Yue, Yoshiko Yokota, and Go Matsuba, “Polyelectrolyte-Layered Hydrogels with Electrically Tunable Toughness, Viscoelasticity, Hysteresis, and Crack Resistance”, Macromolecules, 55, 4, 1230-1238 (2022). Peer-reviewed.
   DOI: 10.1021/acs.macromol.1c02137
   Published online: 27 Jan. 2022.
   A03/A03 Collaboration.
2. *Youfeng Yue and *Jian Ping Gong, “Structure and Unique Functions of Anisotropic Hydrogels Comprising Uniaxially Aligned Lamellar Bilayers”, Bull. Chem. Soc. Jpn., 94, 2221-1/14 (2021). Peer-reviewed, Open Access.
   DOI: 10.1246/bcsj.20210209
   Published online: 20 Jul. 2021.
   Inside Cover.

A03研究代表者　上野祐子  /  A03 Principal Investigator, Yuko Ueno